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Energy expenditure and body composition in Prader-Willi syndrome

In this study, perinatal outcomes for women with 75 g OGTT results that were positive by HAPO 1.75 OR thresholds (Diabetes Canada alternative) were compared to women with 75 g OGTT results that were positive by HAPO 2.0 OR thresholds (Diabetes Canada preferred)

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Similarly, the highly anticipated EVOKE and EVOKE+ phase 3 trials of oral semaglutide in early Alzheimers disease reported in November 2025 that semaglutide failed to meet its primary endpoints : while it reduced several AD-related biomarkers by up to 10%, these changes did not translate into cognitive or functional benefit ( [72] )

Intrahepatic Effects of Incretins Treatment with GLP-1RA limits the harmful effects of lipotoxicity and consequently the progression of MASLD, due to their ability to regulate blood glucose levels and improve insulin sensitivity

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